Gene | BRCA2 |
Variant | any |
Transcript ID (GRCh37/hg19) | ENST00000544455 |
Germline/Somatic? | Somatic |
Tumor Type | Primary Site |
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Some mutations in BRCA2 may be associated with sensitivity to PARP inhibitors. The effect of this missense mutation is not entirely clear. Drug: Rucaparib Niraparib Olaparib
This gene is a known cancer gene.