|Variant||Gene||Type||COSMIC ID||DNA Change (Coding Nucleotide)||Exon|
|ARID1A copy number gain||ARID1A||CNV|
|ARID1A copy number loss||ARID1A||CNV|
|ARID1A any mutation||ARID1A||any|
This gene is a known cancer gene.
This gene is a known cancer gene. ARID1A/BAF250A subunit of the SWI/SNF (BAF) chromatin remodeling complex has emerged as recurrently mutated in a broad array of tumor types and a potential tumor suppressor. There is evidence indicating that ARID1A-mutated cancers may be subjected to therapeutic intervention.