|Amino Acid Change||P263T|
|Transcript ID (GRCh37/hg19)||ENST00000263923|
|Tumor Type||Primary Site|
KDR encodes the protein VEGF2, a receptor tyrosine kinase that regulates angiogenesis and vascular development. While KDR mutations are rare, amplification or protein overexpression have been reported in small proportion of a variety of solid tumors. KDR P263T has not been characterized and the effect on protein function is unknown. These results should be interpreted in the clinical context.