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MAP2K1
Information
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MAP2K1 C121S
Gene
MAP2K1
Variant
missense
Amino Acid Change
C121S
Transcript ID (GRCh37/hg19)
ENST00000307102
Codon
121
Germline/Somatic?
Somatic
Pertinent Negative In
Tumor Type
Primary Site
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MAP2K1
Variants
MAP2K1 C121S
Primary Sites
Blood
Bone Marrow
Lymph Node
Tumor Types
Hairy Cell Leukemia
Follicular Lymphoma
Langerhans Cell Histiocytosis
Interpretation
The p.C121S mutation has been associated with resistance to mutant BRAF inhibitors.
Last updated: 2017-01-20 03:31:52 UTC
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