Gene | KRAS |
Variant | any |
Transcript ID (GRCh37/hg19) | ENST00000256078 |
Codon | 12 |
Exon | 2 |
Genomic Coordinates (GRCh37/hg19) | 12:25398283-25398285 |
Germline/Somatic? | Somatic |
Tumor Type | Primary Site |
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KRAS belongs to the RAS family of oncogenes. KRAS mutations have been described in approximately 3-40% gall bladder adenocarcinomas (more often in East Asia). The prognostic and therapeutic implications of KRAS mutations in gall bladder adenocarcinomas continue to be explored.