EGFR G863D
| Gene | EGFR |
| Variant | missense |
| Amino Acid Change | G863D |
| Transcript ID (GRCh37/hg19) | ENST00000275493 |
| Codon | 863 |
| Exon | 21 |
| Germline/Somatic? | Somatic |
Pertinent Negative In
| Tumor Type | Primary Site |
|---|
Interpretations
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Interpretation
A low frequency mutation detected in lung and gastric cancer. Functional significance of this alteration has not yet been described. However, a single NSCLC patient with this mutation in a clinical trial shows partial response to gefitinb therapy
Last updated: 2015-12-09 20:16:16 UTC
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