Gene | BRAF |
Variant | insertion |
Amino Acid Change | T599_V600insT |
Transcript ID (GRCh37/hg19) | ENST00000288602 |
Codon | 599-600 |
Exon | 15 |
Germline/Somatic? | Somatic |
Tumor Type | Primary Site |
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BRAF mutants, with a 3bp insertion between codons 599 and 600, display increased in vitro kinase activity activation potential comparable to those of BRAF V600E mutants.