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Interpretation 355
Tier 1
ERBB4
Variants
Primary Sites
Skin
Tumor Types
Melanoma
Interpretation

Melanomas with ERBB4 mutations may be associated with sensitivity to Lapatinib.

Citations
  1. Prickett TD, et al. Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. Nat Genet 2009;41(10):1127-32
  2. Davies MA, et al. Analysis of the genome to personalize therapy for melanoma. Oncogene 2010;29(41):5545-55
Last updated: 2017-01-20 03:41:12 UTC
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When using PMKB, please cite: Huang et al., JAMIA 2017

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