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ERBB2 T798I
GeneERBB2
Variantmissense
Amino Acid ChangeT798I
Transcript ID (GRCh37/hg19)ENST00000269571
Codon798
Germline/Somatic?Somatic
Pertinent Negative In
Tumor TypePrimary Site
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ERBB2
Variants
ERBB2 T798I
Primary Sites
Breast
Tumor Types
Adenocarcinoma
Interpretation

An acquired HER2 gatekeeper mutation induces resistance to neratinib in a patient with HER2 mutant-driven breast cancer

Last updated: 2017-03-08 21:32:18 UTC
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Disclaimer: You assume full responsibility for all risks associated with using this PMKB website. The Englander Institute for Precision Medicine at Weill Cornell Medicine makes no guarantee of the comprehensiveness, reliability or accuracy of the information on this website and assumes no responsibility for errors in the information associated with this web site. Healthcare providers and patients must integrate all clinical and laboratory findings as well as information from a variety of sources before deciding on appropriate clinical care options.

When using PMKB, please cite: Huang et al., JAMIA 2017

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