EGFR D761Y
| Gene | EGFR |
| Variant | missense |
| Amino Acid Change | D761Y |
| Transcript ID (GRCh37/hg19) | ENST00000275493 |
| Codon | 761 |
| Exon | 19 |
| Germline/Somatic? | Somatic |
Pertinent Negative In
| Tumor Type | Primary Site |
|---|
Interpretations
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Interpretation
The EGFR D761 mutation is associated with acquired resistance to EGFR-TKIs (Balak et al., 2006). The functional significance of this alteration is being investigated.
Last updated: 2015-12-09 20:16:10 UTC
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