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Interpretation 342
Tier 1
PTCH1
Variants
PTCH1 W844C
Primary Sites
Skin
Tumor Types
Basal Cell Carcinoma
Interpretation

The W844C mutation is associated with resistance to Vismodegib in basal cell carcinoma.

Citations
  1. Sandhiya S, et al. The dawn of hedgehog inhibitors: Vismodegib. J Pharmacol Pharmacother 2013;4(1):4-7
Last updated: 2017-01-20 03:36:39 UTC
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When using PMKB, please cite: Huang et al., JAMIA 2017

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