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Interpretation 2207
Tier 1
KIT
Variants
KIT N505I
Primary Sites
Unknown
Tumor Types
Thymic Carcinoma
Gastrointestinal Stromal Tumor
Interpretation
Sorafenib
Citations
Montemurro M, et al. Sorafenib as third- or fourth-line treatment of advanced gastrointestinal stromal tumour and pretreatment including both imatinib and sunitinib, and nilotinib: A retrospective analysis. Eur J Cancer 2013;49(5):1027-31
Park SH, et al. Sorafenib in patients with metastatic gastrointestinal stromal tumors who failed two or more prior tyrosine kinase inhibitors: a phase II study of Korean gastrointestinal stromal tumors study group. Invest New Drugs 2012;30(6):2377-83
Bisagni G, et al. Long lasting response to the multikinase inhibitor bay 43-9006 (Sorafenib) in a heavily pretreated metastatic thymic carcinoma. J Thorac Oncol 2009;4(6):773-5
Last updated: 2018-04-18 13:25:13 UTC
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Genes
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Tumor Types
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Activity