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Interpretation 2186
Tier 1
KIT
Variants
KIT P551_M552del
Primary Sites
Unknown
Tumor Types
Gastrointestinal Stromal Tumor
Thymic Carcinoma
Interpretation

Sunitinib

Citations
  1. Demetri GD, et al. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet 2006;368(9544):1329-38
  2. George S, et al. Clinical evaluation of continuous daily dosing of sunitinib malate in patients with advanced gastrointestinal stromal tumour after imatinib failure. Eur J Cancer 2009;45(11):1959-68
  3. Reichardt P, et al. Clinical outcomes of patients with advanced gastrointestinal stromal tumors: safety and efficacy in a worldwide treatment-use trial of sunitinib. Cancer 2015;121(9):1405-13
  4. Thomas A, et al. Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: an open-label phase 2 trial. Lancet Oncol 2015;16(2):177-86
  5. Strobel P, et al. Sunitinib in metastatic thymic carcinomas: laboratory findings and initial clinical experience. Br J Cancer 2010;103(2):196-200
Last updated: 2018-04-18 13:09:11 UTC
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When using PMKB, please cite: Huang et al., JAMIA 2017


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