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BRAF
Information
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Pending Review
Interpretation 2165
Tier 1
BRAF
Variants
BRAF D594N
Primary Sites
Unknown
Tumor Types
Melanoma
Interpretation
Trametinib
Citations
Yao Z, et al. BRAF Mutants Evade ERK-Dependent Feedback by Different Mechanisms that Determine Their Sensitivity to Pharmacologic Inhibition. Cancer Cell 2015;28(3):370-83
Heidorn SJ, et al. Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF. Cell 2010;140(2):209-21
Last updated: 2018-04-06 15:11:17 UTC
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