BRAF codon(s) 600 any
|Tumor(s)||Histiocytic and Dendritic Cell Neoplasms|
Recent studies have reported the BRAF mutation in a subset of histiocytic tumours. BRAF pathway may contribute to the pathogenesis or malignant transformation of histiocytic and dendritic cell neoplasms.
Go et al Frequent detection of BRAF V600E mutations in histiocytic and dendritic cell neoplasms Histopathology 2014, 65, 261–272.
Idbaih et al Dramatic response of a BRAF V600E-mutated primary CNS histiocytic sarcoma to vemurafenib. Neurology. 2014 Oct 14;83(16):1478-80
Michonneau et al...BRAF(V600E) mutation in a histiocytic sarcoma arising from hairy cell leukemia.J Clin Oncol 2014 Dec 24;32(35)
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